Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the
developing rhesus monkey retina. Krueger M.R., Fishman-Williams
E., Simo S, Tarantal A., and La Torre A.
Differentiation (2023)
Mechanical Disruption of the Inner Limiting Membrane In Vivo
Enhances Targeting to the Inner Retina. Do J.L., Pedroarena-Leal
N., Louie M., Avila Garcia P., Alnihmy A., Patel A., Weinreb
R.N., Wahlin K.J., La Torre A., and Welsbie D.S.
IOVS (2023)
Osteopontin drives retinal ganglion cell resiliency in
glaucomatous optic neuropathy. Zhao M., Toma K, Kinde B., Li L.,
Patel A.K., Wu K.Y., Lum M.R., Tan C., Hooper J.E., Kiregstein
A.R., La Torre A., Liao Y.J., Welsbie D.S., Hu
Y, Han Y. Duan X. Cell reports (2023)
Retinal ganglion cell repopulation for vision restoration in
optic neuropathy: a roadmap from the RResTORe Consortium. Soucy
J.R and RResTORe Consortium. Molecular
neurodegeneration (2023)
The importance of unambiguous cell origin determination in
neuronal repopulation studies. Johnson T.V., Calkins D.J.,
Fortune B., Goldberg J.L., La Torre A., Lamba
D.A., Meyer J.S., Reh T.A., Wallace V.A., Zack D.J., Baranov P.
iScience (2023)
Notch directs telencephalic development and controls neocortical
neuron fate determination by regulating microRNA levels. Han
J.S., Fishman-Williams E., Decker S.C., Brown N.L., Simo S., and
La Torre A. Development (2023)
The E3 ubiquitin ligase CRL5 regulates dentate gyrus
morphogenesis, adult neurogenesis, and animal behavior. Reyes
R.V., Hino K., Canales C.P., Dickson E.J., La Torre
A., and Simo S. Frontiers in Neuroscience (2022)
Retinal organoids derived from rhesus macaque iPSCs undergo
accelerated differentiation compared to human stem cells. Lopez
A.J., Kim S., Qian X., Roger K., Stout J.T., Thomasy S.M.,
La Torre A., Chen R., Moshiri A. Cell
Proliferation (2022)
Solving neurodegeneration: Common mechanisms and strategies for
new treatments. Wareham L.K., Liddlelow S.A., Temple S., Benowitz
L.I., Di Polo A., Wellington C., Goldberg J.L., He Z., Duan X.,
Bu G., Davis A.A., Shekhar K., La Torre A., Chan
D.C., Canto-Soler V.M., Flanagan J.G., Subramanian P., Rossi S.,
Brunner T., Bovenkamp D.E., Calkins D.J. Molecular
neurodegeneration (2022)
Oscillatory behaviors of microRNA networks: emerging roles in
retinal development. Fishman E.S., Han J.S., and La Torre
A. Frontiers in Cell and Developmental biology (2022)
MicroRNA signatures of the developing primate fovea. Fishman
E.S., Louie M., Miltner A.M., Cheema S.K., Wong J., Schlaeger
N.M., Moshiri A., Simó S., Tarantal A.F., and La Torre
A. Frontiers in Cell and Developmental Biology (2021)
Inhibition of GCK-IV kinases dissociates cell death and axon
regeneration signaling in CNS neurons. Patel A.K, Broyer R.,
Cassidy D.L., Louie M.J., Tianlun L., La Torre
A., Hassan A., Mitchell K.L., Jasula-Ranga V., Hu Y.,
Duan X., Vilar S., Bixby K.L, Weinreb R.N., Lemmon V.O., Zack
D.J., and Welsbie D.S. Proc. Natl. Acad. Sci. U.S.A. (2020)
CRL5-dependent regulation of Arl4c signaling controls pyramidal
neuron migration and dendritogenesis in the developing
hippocampus. Han J.S, Hino K, Reyes R., Canales C.P.,
Miltner A.M., Camarena Y.M., Haddadi Y., Sun J., Chen
C.Y., La Torre A., and Simo S. Proc.
Natl. Acad. Sci. U.S.A. Sep 15;117(37):23073-23084
PMID: 32873638
Pereiro X, Miltner AM, La Torre
A*, Vecino E*. Effects of Adult Müller Cells
and Their Conditioned Media on the Survival of Stem Cell-Derived
Retinal Ganglion Cells. 2020 Jul 22;9(8):1759. doi:
10.3390/cells9081759. PMID: 32708020 *Co-senior authors
Parcerisas A., Pujadas Ll., Ortega A., Perelló-Amorós B., Viais
R., Hino K., Figueiro-Silva J., La Torre A.,
Trullás R., Simo S., Lüders J., Soriano E. NCAM2 regulates
dendritic and axonal differentiation through the cytoskeletal
proteins MAP2 and 14-3-3gz. May 18;30(6) 2020.
Cerebral Cortex
Fairchild C.L.A., Cheema S.K., Wong J., Simo S. and La
Torre A. Let-7 regulates cell cycle dynamics in the
developing cerebral cortex and retina. Scientific
Reports Oct 25;9(1):15336 (2019). PMID: 31653921
Miltner A.M., Mercado-Ayon Y., Cheema S.K., Zhang P., Zawadzki
R.J. and La Torre A. A novel reporter
mouse uncovers endogenous Brn3b expression. International
Journal of Molecular Sciences Jun 14;20(12) (2019). PMID:
31197108
Miltner AM, La
Torre A. Retinal Ganglion Cell Replacement:
Current Status and Challenges Ahead. Dev Dyn. September 21
(2018)
Fairchild CL, Hino K, Han JS, Miltner AM, Peinado
Allina G, Brown CE, Burns ME, La
Torre A*, Simó S*RBX2 maintains final retinal cell
position in a DAB1-dependent and -independent fashion.
Development. Feb 2 (2018) *Co-senior authors
Akina Hoshino, Rinki Ratnapriya, Matthew J.
Brooks, Vijender Chaitankar, Matthew S.
Wilken, Chi Zhang, Margaret R. Starostik, Linn
Gieser, Anna La Torre, Mario
Nishio, Olivia Bates, Ashley Walton, Olivia
Bermingham-McDonogh, Ian A. Glass, Rachel O.L.
Wong, Anand Swaroop, Thomas A. Reh. Molecular
Anatomy of the Developing Human Retina. Developmental Cell.
December 18 (2017)
Anna La Torre. Retinal Differentiation of
Mouse Embryonic Stem Cells. Bio-protocol. July 5
(2016).
Anna La Torre, Akina Hoshino, Christopher
Cavanaugh, Carol B. Ware and Thomas A. Reh. The GIPC1-Akt1
pathway is required for the specification of the eye field in
mouse embryonic stem cells. Stem Cells. May 26 (2015).
Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox
KE, Reh TA, Vetter ML. Ezh2 maintains retinal progenitor
proliferation, transcriptional integrity, and the timing of late
differentiation. Dev Biol. May 16 (2015). PMID: 25989023
Wilken M.S.; Brzezinski J.A.; La Torre A.;
Siebenthall K.; Thurman R.; Sabo P.; Sandstrom R.S.; Vierstra J.;
Canfield T.K.; Hansen R.S.; Bender M.A.; Stamatoyannopoulos J.;
Reh T.A. DNase I hypersensitivity analysis of the mouse brain and
retina identifies region-specific regulatory elements.
Epigenetics Chromatin. Feb 28 (2015). PMID: 25972927
La Torre A.; Georgi S.A. and Reh T.A. A
conserved miRNA pathway regulates developmental timing of retinal
neurogenesis. Proc Natl Acad Sci U S A. Jun 10 (2013). PMID:
23754433
La Torre A.; Masdeu M.; Cotrufo T; Moubarak
R.S.; del Río J.A.; Comella J.X.; Soriano E. and Urena J.M. A
role for the tyrosine kinase Ack1 in Neurotrophin Signaling and
Neuronal Extension and branching. Cell Death Dis. April 18
(2013). PMID: 23598414
Quintana A.; Sanz E.; Wang W.; Storey G.P.; Güler A.D.; Wanat
M.J.; Roller B.A.; La Torre A.; Amieux P.S.;
McKnight G.S.; Bamford N.S and Palmiter R.D. Lack of GPR88
enhances medium spiny neuron activity and alters motor- and cue-
dependent behaviors. Nat Neurosci. October 14 (2012). PMID:
23064379
La Torre A.; Lamba D.A.; Jayabalu A. and Reh
T.A. Production and transplantation of retinal cells from human
and mouse embryonic stem cells. Methods Mol. Biol. (2012). PMID:
22688710
Simó, S., Pujadas L., Segura M.F., La Torre A.,
Del Rio J.A., Urena J.M., Comella J. X., and Soriano E. (2007).
Reelin induces the detachment of postnatal subventricular zone
cells and the expression of the Egr-1 through Erk1/2 activation.
Cereb Cortex. 17:294-303.
La Torre A.; Del Río J.A.; Soriano E. and Ureña
J.M. Expression pattern of Ack1 during brain development in
mouse. Gene Expression Patterns, May 31 (2006). PMID: 16750431
Urena J.M.; La Torre A.; Martínez A.; Lowenstein
E.; Franco N.; Winsky- Sommerer R.; Fontana X.; Casaroli R.;
Ibáñez M.A.; Pascual M.; Del Río J.A.; de Lecea L. and Soriano E.
Expression, synaptic localization and developmental regulation of
Ack1/Pyk1: a cytoplasmic tyrosine kinase highly expressed in
adult and developing brain. Journal of Comparative Neurology 490,
119-132 (2005). PMID: 16052498
Gonzalez-Billault, C., Del Rio J.A., Urena J.M., Jimenez-Mateos
E.M., Barallobre M.J., Pascual M., Pujadas L., Simó S., La Torre
A., Gavin R., Wandosell F., Soriano E., and J. Avila J. (2005). A
role of MAP1B in Reelin-dependent neuronal migration. Cereb
Cortex. 15:1134-45.
Del Rio, J.A., Gonzalez-Billault C., Urena J.M., Jimenez E.M.,
Barallobre M.J., Pascual M., Pujadas L., Simó S., La
Torre A., Wandosell F., Avila J., and Soriano E. (2004).
MAP1B is required for Netrin1 signaling in neuronal migration and
axonal guidance. Curr Biol. 14:840-50.
